Proteases (E1101): What the Sources Found

Proteases (papain, bromelain, ficin) is the additive the food industry lists as E1101. In our table it is no risk identified: it takes no points off a product's score for a child.

In short

No risk identified. No regulator finding we score, so a product keeps all 33 additive points.
No child flag. Nothing below is written about children specifically, so the class is the same at every age.
3 citations from EFSA, Law, FDA, each one below.

What Proteases does to a score

A packaged food starts with 33 points for what is in its ingredient list. Proteases takes no points off a product's score. Scan the pack in Sito and the score you get is the one for your own child's age, with this additive named in the reasons. How we score has the whole method.

What the sources found

Every classification in our table comes from the citations below, and nothing else. They are quoted as the source wrote them.

EFSA 10.2903/j.efsa.2026.9837 (EFSA Journal 2026;24(1):9837 — Safety evaluation of the food enzyme papain from the latex of Carica papaya L.)
'the Panel concluded that there is no concern for genotoxicity of the food enzyme papain'; 'the food enzyme papain extracted from the latex of the unripe C. papaya L. does not give rise to safety concerns under the intended conditions of use'; and 'a risk of allergic reactions upon dietary exposure to this food enzyme, particularly for papaya, ananas, kiwi, soy, fig and pollen allergic individuals, cannot be excluded'.
Law Regulation (EC) No 1333/2008, Article 34 (Transitional provisions), consolidated text 02008R1333 — EN — 16.12.2024 — 059.001 (EUR-Lex ELI: reg/2008/1333)
Food enzymes are governed by Regulation (EC) No 1332/2008, not the additives Regulation: 'the authorisations for E 1103 Invertase and E 1105 Lysozyme laid down in Directive 95/2/EC shall be repealed with effect from the date of application of the Community list on food enzymes in accordance with Article 17 of Regulation (EC) No 1332/2008'. A search of the full consolidated text returns no E 1101 entry in Annex II or Annex III — absence by jurisdiction, not by refusal.
FDA 21 CFR 184.1585 (Papain) — Part 184 "Direct Food Substances Affirmed as Generally Recognized as Safe"; verified against the current eCFR structure
Papain (CAS Reg. No. 9001-73-4), the proteolytic enzyme from Carica papaya, is affirmed GRAS as a direct human food ingredient for use as an enzyme, processing aid and texturizer.

Why this class

Clean current EFSA and FDA status. These rows exist so that an unfamiliar additive is never treated as a bad one: a missing row costs a product nothing, and a clean row says so with citations.

Our confidence in this row's classification is high. Medium or low does not mean the evidence is weak; it means something about the row is still being pinned down, usually a regulatory status confirmed from one source rather than two.