Disodium guanylate (E627): What the Sources Found

Disodium guanylate is the flavour enhancer the food industry lists as E627. In our table it is no risk identified: it takes no points off a product's score for a child.

In short

No risk identified. No regulator finding we score, so a product keeps all 33 additive points.
No child flag. Nothing below is written about children specifically, so the class is the same at every age.
2 citations from FDA, EFSA, each one below.

What Disodium guanylate does to a score

A packaged food starts with 33 points for what is in its ingredient list. Disodium guanylate takes no points off a product's score. Scan the pack in Sito and the score you get is the one for your own child's age, with this additive named in the reasons. How we score has the whole method.

What the sources found

Every classification in our table comes from the citations below, and nothing else. They are quoted as the source wrote them.

FDA 21 CFR 172.530 (govinfo CFR-2024-title21-vol3-sec172-530)
Disodium guanylate may be safely used as a flavour enhancer in food at a level not in excess of that reasonably required to produce the intended effect.
EFSA Call for data for the re-evaluation of ribonucleotides (E 626-635), 2023-06-28
E 627 is inside the open ribonucleotide re-evaluation; no EFSA opinion, ADI or age-group exposure assessment exists yet.

Why this class

Clean current EFSA and FDA status. These rows exist so that an unfamiliar additive is never treated as a bad one: a missing row costs a product nothing, and a clean row says so with citations.

Our confidence in this row's classification is medium. Medium or low does not mean the evidence is weak; it means something about the row is still being pinned down, usually a regulatory status confirmed from one source rather than two.